Arizona Cardinals vs Indianapolis Colts Betting Tips, Prediction & Odds

After a surprising loss last week, the Arizona Cardinals will have another chance to clinch a playoff berth as they host the Indianapolis Colts at State Farm Stadium in Glendale in AZ, on Christmas Day.               

Match Details 

  • Arizona Cardinals vs Indianapolis Colts
  • NFL – Regular season
  • Date – 25/12/2021
  • Starting time – 8:15 PM ET
  • Venue: State Farm Stadium, Glendale, AZ

Arizona Cardinals Stats & Form

Arizona CardinalsThe Arizona Cardinals are coming into Saturday night’s game with a 10-4 record and with a win will book their ticket for the playoffs. The Cardinals have lost the last two games, 30-23 to the Los Angeles Rams and 30-12 last week against the Detroit Lions.

Arizona started the day tied for the NFL’s best record, undefeated on the road and a win away from ending a six-year postseason drought. Kyler Murray couldn’t get away from the scrappy Lions when he tried to run, finishing with 3 yards rushing on four carries, against a scheme set up by defensive coordinator Aaron Glenn. By the time Murray threw a touchdown pass, there was 4:40 left in the game and Arizona trailed by 15 points.

Since starting 7-0, the Cardinals have lost four of their past seven games.

Arizona Cardinals News

DE Jordan Phillips and P Andy Lee have been ruled out for Christmas Day while James Conner and Rondale Moore are questionable.

Indianapolis Colts Stats & Form

Indianapolis ColtsThe Indianapolis Colts are second in the AFC North with an 8-6 record and are still in the playoff run. The Colts have won five of the last six games, including a 27-17 win over the Patriots last weekend.

Jonathan Taylor rushed for 170 yards, including a 67-yard touchdown run with 2:01 left to seal Indy’s victory. Taylor’s performance may have changed their season as well. By winning for the fifth time in six games and snapping an eight-game losing streak against a bitter rival, the Colts solidified its playoff hopes with another crucial conference victory.

He’s run for a score in 11 straight games, tying Hall of Famer Lenny Moore for the longest streak in franchise history. EJ Speed became the first NFL player to record two touchdowns off blocked punts in one season since Ed Reed in 2003.

Taylor already has 1,518 yards rushing this season and needs one more 100-yard game to tie Edgerrin James for the second most in team history in one season.

Indianapolis Colts News

S Andrew Sendejo, G Mark Glowinski, C Ryan Kelly, DE Kemoko Turay and CB Rock Ya-Sin will not suit up against Arizona.

Arizona Cardinals vs Indianapolis Colts Head-to-Head Stats

These two teams have faced each other only five times in the last 25 years. The Colts lead the series 3-2 but the Cardinals have won the last two games. Their most recent matchup was in 2017 when Arizona won 16-13 in overtime.

Arizona Cardinals vs Indianapolis Colts Betting Odds

The odds for winning this one are as close as they can be. Arizona is at -116 while the Colts are at -106.

The total point margin is set at 48.5 with -105 for over and -125 for under.

Betting Tip

The Indianapolis Colts definitely have the momentum. They are coming off a huge win over the New England Patriots while Arizona lost to the worst team in the league. The Cardinals were second in the league in defense DVOA through Week 9 of the season but since Week 10 they rank 15th. Their offense has also regressed, scoring a touchdown on just 33.3% of their trips inside the red zone since Murray came back from an ankle injury at the beginning of the month.

The Colts have turned things up on both sides of the ball, with their stop unit ranking fourth in the league in defense DVOA since Week 10, while their offense ranks fifth in EPA/play and sixth in Success Rate over the same period of time. The Cardinals are 3-3 at home and the Colts 4-2 on the road. All this leads to the conclusion that Indianapolis will win on Christmas Day.

  • Tip Quote (Home team win): -116 by 22bet
  • Tip Quote (Away team win): -106 by 22bet
  • Expert betting tip: Indianapolis Colts to win (-106 by 22bet)